Research
PubMed Central(PMC)
A free full-text archive of biomedical and life sciences journal literature at the U.S. National Institutes of Health’s National Library of Medicine
ClinicalTrials.gov
A repository of all the clinical trials going on in the U.S. or around the world. Search for “new daily persistent headache,” or ” NDPH ” or “headache” or “chronic pain” to find potentially useful trials near you. You can also filter results by location and age of accepted participants.
Google Scholar
Please use search for “new daily persistent headache,” or ” NDPH ” or “headache” or “chronic pain” to find articles, studies and research.
Toward a better understanding of persistent headache after mild COVID‐19: Three migraine‐like yet distinct scenarios
One year after the outbreak of coronavirus disease 2019 (COVID‐19), referrals for persistent headache, often defined as “post‐COVID headache,” have become increasingly common in outpatient headache clinics.
Therapeutic Response for NDPH by a Tumor Necrosis Factor Alpha Antagonist, Lithium
New daily persistent headache (NDPH) is an uncommon, treatment-resistant primary headache disorder that was first describe by Vanast in 1986 as a benign syndrome. Elevated TNF-alpha levels on CSF of NDPH patients as a possible cause of this disease.
A Qualitative Study of the Experiences of Patients With New NDPH
Three main themes were identified: (1) the origin of the illness and seeking answers; (2) characteristics of the pain; and (3) the impact of pain on patients’ lives. The patients precisely recalled the time of onset and the trigger of the pain.
Memantine Ameliorates Migraine Headache
A significant number of migraine patients do not find effective and safe treatment to reduce the frequency and severity of their migraine attacks. Hence, a need for newer therapeutic agent exists. In this study, we examined the efficacy and safety of memantine for the...
New daily persistent headache: a systematic review on an enigmatic disorder
New daily persistent headache (NDPH) presents with a sudden onset headache which continues without remission within 24 h.
Resolution of NDPH by a Tumor Necrosis Factor Alpha Antagonist
New daily persistent headache is a continuous, unremitting headache, notorious for its unresponsiveness to aggressive medical interventions. The underlying pathophysiology of new daily persistent headache is poorly understood resulting in unending, chronic pain.
Because NDPH is a rare and heterogeneous condition, getting funding for research is nearly impossible. Most clinical trials that could potentially help NDPH sufferers are focused on migraine, tension headache, or chronic pain in general.
Still, here is a list of studies that have shown potentially promising treatments for NDPH (if you have a study that you think should be included on this page, use the contact form below to submit it)