A free full-text archive of biomedical and life sciences journal literature at the U.S. National Institutes of Health’s National Library of Medicine
A repository of all the clinical trials going on in the U.S. or around the world. Search for “new daily persistent headache,” or ” NDPH ” or “headache” or “chronic pain” to find potentially useful trials near you. You can also filter results by location and age of accepted participants.
Please use search for “new daily persistent headache,” or ” NDPH ” or “headache” or “chronic pain” to find articles, studies and research.
Phenotype of new daily persistent headache: subtypes and comparison to transformed chronic daily headache
It is unknown whether new daily persistent headache (NDPH) is a single disorder or heterogenous group of disorders, and whether it is a unique disorder from chronic migraine and chronic tension-type headache.
Brain structure and cortical activity changes of new daily persistent headache: multimodal evidence from MEG/sMRI
New daily persistent headache (NDPH) is a rare but debilitating primary headache disorder that poses a significant burden on individuals and society. Despite its clinical importance, the underlying pathophysiological mechanisms of NDPH remain unclear.
Comparison of continuous headache features in youth with migraine, new daily persistent headache, and persistent post-traumatic headache
To compare clinical features in youth with continuous headache with migraine, persistent post-traumatic headache (PPTH), and new daily persistent headache (NDPH) to determine if they are similar, contrary to their distinction in the International Classification of...
Alterations in regional homogeneity and multiple frequency amplitudes of low-frequency fluctuation in patients with new daily persistent headache: a resting-state functional magnetic resonance imaging study
Patients with NDPH may have abnormal activation of the visual system. Abnormal visual activation may occur mainly in higher frequency band of the classical band. No sex differences in brain activity were found in patients with NDPH.
Daily persistent headache with nutcracker physiology and spinal epidural venous congestion: Treatment with lumbar vein embolization
Nutcracker phenomenon (NCP) can cause various congestion syndromes secondary to the superior mesenteric artery (SMA) compressing the left renal vein (LRV) resulting in venous reflux.
Regarding clinical presentation, long COVID headache can manifest with a clinical picture similar to that of the new daily persistent headache, classified as NDPH in the ICHD-3, because of its prominent temporal relationship and resistance to treatment.
Because NDPH is a rare and heterogeneous condition, getting funding for research is nearly impossible. Most clinical trials that could potentially help NDPH sufferers are focused on migraine, tension headache, or chronic pain in general.
Still, here is a list of studies that have shown potentially promising treatments for NDPH (if you have a study that you think should be included on this page, use the contact form below to submit it)